芹甙元-7-葡萄糖苷

芹甙元-7-葡萄糖苷

分类: 植物提取物 阅读

芹甙元-7-葡萄糖苷

芹甙元-7-葡萄糖苷 用途与合成方法
生物活性Apigenin-7-glucoside (Apigenin-7-O-β-D-glucopyranoside),ROS 清除剂,具有抗增殖,抗氧化活性。
体外研究

Apigenin 7-glucoside exhibits significant anti-proliferative activity against B16F10 melanoma cells after 24 and 48 h of incubation. Apigenin-7-glucoside provoks an increase of subG0/G1, S and G2/M phase cell proportion with a significant decrease of cell proportion in G0/G1 phases. Apigenin-7-glucoside enhances melanogenesis synthesis and tyrosinase activity of B16F10 melanoma cells.
Apigenin 7-glucoside specifically induces the differentiation of CD34 + cells towards the erythroid lineage and inhibited the myeloid differentiation. Apigenin 7-glucoside has strong antioxidant activity against reactive oxygen species (ROS) in vitro in a concentration-dependent manner.

化学性质 白色结晶体,可溶于甲醇、乙醇、DMSO等有机溶剂,来源于广藿香、仙鹤草,蓰草,构树叶。
用途 用于含量测定/鉴定/药理实验等。
药理药效:抗肿瘤、消炎、抗病毒。
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